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Democratic lawmakers leading an impeachment inquiry against President Donald Trump have heard days of testimony from a parade of senior government officials. In the end, it may not matter, some Democratic lawmakers said, because the other officials who have testified, Trump's own statements, a trove of texts between top U.S. diplomats, and other White House documents have largely substantiated the whistleblower's complaint that Trump pressured Ukraine to investigate political rival Joe Biden.

All is fair in love and…selfies?

Jenna recently announced she was expecting her first child with new boyfriend Steve Kazee.

Alberta's environment minister says Swedish climate activist Greta Thunberg "doesn't understand" the province, and signalled the government won't be laying out the welcome mat for the 16-year-old's upcoming visit.Speaking to reporters outside the Alberta Legislature on Tuesday, Environment Minister Jason Nixon said Thunberg hasn't reached out to the UCP government, and the government has no plans to contact her."I do hope that if she does come to our beautiful province, she takes the time to talk to our state-of-the-art industry partners, who are working tirelessly to continue to produce the most ethical and environmentally friendly oil and gas products in the world," Nixon said."When you look at some of Ms. Thunberg's comments, she doesn't understand our province," Nixon said later, adding Thunberg needs to realize that Alberta must be an active partner in any global climate-change strategy.On Saturday, Thunberg announced on Twitter she will travel to Alberta after a series of appearances in the United States.Edmonton Mayor Don Iveson used the same medium Tuesday morning to extend a welcome to the climate activist."I'd love to invite you to [Edmonton's] city hall to discuss the Edmonton Declaration and some of the environmentally friendly projects we're working on," Iveson tweeted to her."Regardless of where you visit, I wish you nothing but the best."NDP Leader Rachel Notley said that while she doesn't agree with every idea Thunberg proposes, she agrees "we need to move forward with concrete strategies to reduce our emissions."She also said the UCP government must "stop distracting from the fact that people across the world are concerned about climate change.""We need to be leaders; we don't need to be cowards."

The F1 team has commented on the world champion's recent social media posts that caused concern.

A made-in-Canada medical breakthrough that disappeared from the market because it wasn't profitable is being revived by the National Research Council of Canada (NRC).It's the latest chapter in the saga of Glybera, the world's first approved gene therapy, which also became the world's most expensive drug after it was licensed to a Dutch company and priced at $1 million for a one-time dose.Glybera treats a rare and potentially deadly genetic disorder called lipoprotein lipase deficiency, or LPLD. Canada has the world's largest population of LPLD patients clustered in the Saguenay region of Quebec, where an ancestor with the genetic mutation settled several hundred years ago.People with LPLD lack a critical enzyme that helps their bodies process the fat from food. There is currently no available treatment and no cure. Those with LPLD must avoid most dietary fat to try to prevent painful and dangerous attacks of pancreatitis. The decision to re-develop a Canadian version of Glybera is the result of a serendipitous series of events, beginning when the NRC's director of research and development for translational bioscience happened to be watching CBC's The National  last November. Dr. Danica Stanimirovic was in the process of selecting the first project for a new federally funded program aimed at bringing rare gene and cell therapies to Canadians at an affordable price. Then she saw CBC's feature report telling the story of how Glybera was pulled from the European market after only one commercial sale. The drug was never offered for sale in Canada or the U.S."That really sparked some thinking," she said. "We really have the ability to advance that."So she picked up the phone and called Dr. Michael Hayden in Vancouver. He's the scientist at the University of British Columbia and the BC Children's Hospital whose team developed Glybera. Hayden said he was happy to get the call. "I was thrilled because this represented a unique response to solve a big Canadian problem, particularly for families in Quebec. And I was just thrilled that we could do something as a national effort to achieve this."Made-in-Canada medical breakthroughThe Glybera story started at UBC in the early 1990s, when Hayden and his team discovered the first genetic mutations that caused LPLD. The researchers then developed a method to fix the malfunctioning gene and allow patients to live a nearly normal life. After doing the preliminary research, the Canadian discovery was licensed to a Dutch company called uniQure, which took Glybera through the rigorous clinical trial and approval process.When the treatment was approved by the European Medicines Agency in 2012, it made headlines as the world's first gene therapy - the first treatment that could repair a faulty gene.When it went on sale in Europe in 2015, Glybera quickly made headlines again, this time as the "world's most expensive drug," priced at $1 million for the one-time dose.Dr. Sander van Deventer, uniQure's chief scientific officer, told CBC News last year that the price was a business calculation based on the price of other drugs that treat rare diseases. Many of those drugs cost more than $300,000 per patient per year. Because Glybera is a one-time treatment that keeps working for years, the $1-million price seemed reasonable, he said.Less than two years later, the drug was pulled from the market after only one commercial sale. uniQure has no plans to revive the therapy.Although Hayden discovered the gene mutation and developed the early phase of the treatment, he had no role in the commercialization of his discovery. And that meant he also had no control over the price."You don't determine the outcome, you don't determine its costs," he said. "I'd say what went wrong is that it was very hard to be able to make sure that this got to patients at a reasonable cost."Stanimirovic said the fact that Canada has such a large population of LPLD patients was an important factor in deciding to give Glybera a second chance. "This gene mutation is very prevalent in Canada compared to other places in the world," she said. "For us, it was almost calling us to do something on the manufacturing side for this particular gene therapy."LPLD is rare, affecting one or two out of every million people around the world. But in the Saguenay region of Quebec, where the gene mutation has been passed down through generations, the numbers are 30 times higher. Up to one in 50 people in some communities are carrying the gene mutation. Both parents must have the mutation for a child to inherit the disease.'Astronomical' price in 'pharma-driven model'The ultimate goal of gene therapy is to fix a genetic problem by giving the patient a new gene. Specially engineered viruses are used to deliver the repair gene to the patient's cells. The cost of manufacturing those viruses is often cited as one reason for the high price of therapies. The need to generate pharmaceutical shareholder profits is another factor. "[Gene therapies] are usually targeted to very small patient populations," Stanimirovic said. "It's hard to make them in a typical pharma-driven model because it drives the price of these therapies to astronomical levels."At its facility in Montreal, the NRC has already developed expertise in producing viral vectors that act as the delivery system for gene therapy. Because the scientists will be re-engineering Glybera using new viral vectors, and improving the therapy, any remaining patents will not be an obstacle, Stanimirovic said. The ultimate plan is to develop public sector manufacturing capacity to create not just an affordable version of Glybera but other gene and cell therapies as well. The total federal funding for six projects including Glybera is estimated at about $80 million over seven years."Our goal is to create new partnership models that will create therapies that are more accessible and more affordable," said Stanimirovic. "We hope we can do that through public partnership or public/private partnerships. So the end goal is to really, through this project, develop Canadian capacity to take on subsequent gene therapies."Hayden called the plan a "beautiful Canadian story.""Now we have to translate this into something that will truly be effective for patients in a limited time frame and I'm so excited to do this." We've been fighting for 10 years with doors closed. The possibility that something is coming is encouraging, but yes, it's long. \- Brenda Potter, mother of a 10-year-old with LPLDFor patients suffering from LPLD, the wait is frustrating.Felix Lapointe, a 10-year-old from Repentigny, Que., was five weeks old when his mother learned the terrible news that her son had the potentially deadly genetic disease.Because there is no treatment available right now, he's managing the disease through a strict diet to reduce the risk of dangerous pancreatic attacks. He will have to wait another five years for the first clinical trials of the re-invented Glybera."We'd like it to happen tomorrow morning," said Brenda Potter, Felix's mother. "Still, we're a little used to this. We've been fighting for 10 years with doors closed. The possibility that something is coming is encouraging, but yes, it's long."

The royals are spending five days in the country.